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In a randomized controlled trial in patients with celiac disease, acute gluten exposure caused a 70% increase in intestinal permeability in the placebo group, while no change in permeability was seen in the larazotide group

For determination of the midpoint potentials E of roGFP variants OxD roGFP or, alternatively, the degree of reduction ReD roGFP = 1 OxD roGFP was plotted against the calculated redox potentials of the respective lipoic acid redox buffers and all data points were fitted to a sigmoidal dose-response curve using GraphPadPrism5 (GraphPad Software, www.graphpad.com)

10.1016/j.neuroscience.2014.04.027 3 AlbarracinR.EellsJ.ValterK

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-6 PUFAs, which are rich in the Western diet, can trigger the cytokine response of epithelial cells, which can be limited by GPx4

It is known that glutathione may promote pheomelanin synthesis, inhibit intracellular melanogenic enzymes, and demonstrate antioxidative as well as antiaging effects [2, 3]